The Plexus project was started by Sandro Dernini who accepted the invitation by two Italian architects, Roberto Brambilla and Gianni Longo, to create a new cultural center into a loft of 7.000 sq.ft., at 530 West 25th. Street, in the Chelsea neighbourhood of New York, which was part of a larger real estate complex under development by them. Sandro asked Richard Flood, art critic and at that time book editor and managing editor of the Art Forum Magazine to join them to develop a performance space with maximum flexibility for fostering an international network of dreamers and realists, theoreticians and pragmatists.
The name of “Plexus” came out from a research conducted by a professional marketing firm to identify the proper name and the Plexus logo was made by Fred Troller, one of the best modernist international style graphic designers in New York. 
The programme of the Plexus Performance Space, at 530 W. 25 ST in Chelsea, was opened with the world premiere of "Turtle Dreams" of Meredith Monk followed by performances by Arleen Schloss, Giancarlo Schiaffini, Paolo Buggiani, Gianfranco Mantegna, Mitch Ross and many others.
World Premiere
Mitch Ross M.C of Plexus 6 A Zone for the Next Zone
Paolo Buggiani
Arleen Schloss Giancarlo Schiaffini
Willem Brugman